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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIG3
All Species:
19.7
Human Site:
Y509
Identified Species:
36.11
UniProt:
P49916
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49916
NP_002302.2
1009
112907
Y509
G
M
F
S
E
I
K
Y
D
G
E
R
V
Q
V
Chimpanzee
Pan troglodytes
XP_511409
922
102716
Y457
K
V
A
H
F
K
D
Y
I
P
Q
A
F
P
G
Rhesus Macaque
Macaca mulatta
XP_001113780
1009
112805
Y509
G
M
F
S
E
I
K
Y
D
G
E
R
V
Q
V
Dog
Lupus familis
XP_548265
991
110592
Y510
G
M
F
S
E
I
K
Y
D
G
E
R
V
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
P97386
1015
113000
Y513
G
M
F
S
E
I
K
Y
D
G
E
R
V
Q
V
Rat
Rattus norvegicus
NP_001012011
943
105425
A477
R
R
A
L
S
V
Q
A
S
L
M
T
P
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006215
902
101303
F437
N
G
D
H
F
S
Y
F
S
R
S
L
K
P
V
Frog
Xenopus laevis
NP_001082183
988
110688
Y471
G
M
Y
A
E
I
K
Y
D
G
E
R
V
Q
V
Zebra Danio
Brachydanio rerio
NP_001025345
752
84159
I287
S
A
K
S
L
L
T
I
Q
E
V
D
A
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650187
806
90830
D341
E
I
I
L
V
D
T
D
T
G
A
L
L
P
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27474
773
86292
Y308
E
D
G
Q
I
F
I
Y
S
R
N
Q
E
N
N
Sea Urchin
Strong. purpuratus
XP_786357
875
97201
E410
A
E
A
C
K
S
V
E
M
G
M
R
K
C
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P04819
755
84810
M290
K
M
K
L
I
K
R
M
L
T
A
C
K
G
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.1
97.7
89.4
N.A.
87.3
82.4
N.A.
N.A.
71.3
68.2
55.7
N.A.
34.9
N.A.
23.3
48.4
Protein Similarity:
100
91.1
98.8
92.2
N.A.
91.3
86.4
N.A.
N.A.
78.9
79.6
64.9
N.A.
48.1
N.A.
39.3
62.9
P-Site Identity:
100
6.6
100
100
N.A.
100
0
N.A.
N.A.
6.6
86.6
6.6
N.A.
6.6
N.A.
6.6
13.3
P-Site Similarity:
100
20
100
100
N.A.
100
13.3
N.A.
N.A.
13.3
100
20
N.A.
20
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
24
8
0
0
0
8
0
0
16
8
8
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
8
0
8
0
% C
% Asp:
0
8
8
0
0
8
8
8
39
0
0
8
0
0
0
% D
% Glu:
16
8
0
0
39
0
0
8
0
8
39
0
8
0
0
% E
% Phe:
0
0
31
0
16
8
0
8
0
0
0
0
8
0
8
% F
% Gly:
39
8
8
0
0
0
0
0
0
54
0
0
0
8
8
% G
% His:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
16
39
8
8
8
0
0
0
0
0
8
% I
% Lys:
16
0
16
0
8
16
39
0
0
0
0
0
24
0
0
% K
% Leu:
0
0
0
24
8
8
0
0
8
8
0
16
8
0
8
% L
% Met:
0
47
0
0
0
0
0
8
8
0
16
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
8
0
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
8
24
8
% P
% Gln:
0
0
0
8
0
0
8
0
8
0
8
8
0
39
8
% Q
% Arg:
8
8
0
0
0
0
8
0
0
16
0
47
0
0
0
% R
% Ser:
8
0
0
39
8
16
0
0
24
0
8
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
16
0
8
8
0
8
0
0
0
% T
% Val:
0
8
0
0
8
8
8
0
0
0
8
0
39
8
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _